Additional file 1:

Sequence Data. Excel file with information on all sequences included in study and data from searches. Sheets for Fungi, Metazoa and Plants plus overview for each group. Table contains accession numbers for MutY/M/T orthologous sequences as well as information on BLASTP hit values and domain hits. Bullets symbolize reliable hits for a species to a certain query and may be found in two columns for each Mut protein: "MutX" or "MutX additional refs" when additional query sequences from closely related species have been used. The initially used query sequences are listed in row 2. Comments, such as truncated domains, are listed in "Note" column.

Format: XLS Size: 68KB Download file

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Additional file 2:

MutY alignment. For MutY and MutM most sequences from tables are included. For MutT only fungi and human sequences are included. All sequences are named with a code that identifies the organism group: 'Me' = metazoa; 'Fu' = fungi; 'Pl' = plants; 'Ba' = bacteria. Gaps in all sequences are the result of insertions in sequences removed from alignment. Annotations from literature are added. Secondary structure was taken from predictions using the "PHYRE automatic fold recognition server" (http://www.sbg.bio.ic.ac.uk/phyre/ webcite). Regions that are judged as different in a group of organisms are marked with boxes.

Format: PDF Size: 2.1MB Download file

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Additional file 3:

MutM alignment. For MutY and MutM most sequences from tables are included. For MutT only fungi and human sequences are included. All sequences are named with a code that identifies the organism group: 'Me' = metazoa; 'Fu' = fungi; 'Pl' = plants; 'Ba' = bacteria. Gaps in all sequences are the result of insertions in sequences removed from alignment. Annotations from literature are added. Secondary structure was taken from predictions using the "PHYRE automatic fold recognition server" (http://www.sbg.bio.ic.ac.uk/phyre/ webcite). Regions that are judged as different in a group of organisms are marked with boxes.

Format: PDF Size: 3.2MB Download file

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Additional file 4:

MutT alignment. For MutY and MutM most sequences from tables are included. For MutT only fungi and human sequences are included. All sequences are named with a code that identifies the organism group: 'Me' = metazoa; 'Fu' = fungi; 'Pl' = plants; 'Ba' = bacteria. Gaps in all sequences are the result of insertions in sequences removed from alignment. Annotations from literature are added. Secondary structure was taken from predictions using the "PHYRE automatic fold recognition server" (http://www.sbg.bio.ic.ac.uk/phyre/ webcite). Regions that are judged as different in a group of organisms are marked with boxes.

Format: PDF Size: 245KB Download file

This file can be viewed with: Adobe Acrobat Reader