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Non-homologous end joining and human disease

Edited by: M Hande, Dr Predrag Slijepcevic

Collection published: 22 August 2012

Last updated: 22 March 2013

Non homologous end joining and human disease The series focuses on understanding the mechanisms of non-homologous end joining (NHEJ) in the process of DNA repair and the effects of dysfunctional NHEJ in relation to human disease. It comprises articles showing novel insights into NHEJ pathways and related syndromes, as well as smaller advances contributing to the existing framework of knowledge on NHEJ.

We welcome further original research submissions. Please submit your manuscript through our website and indicate in your covering letter that you would like it to be considered for the series, or alternatively, send a pre-submission enquiry to editorial@genomeintegrity.com


Review   Open Access

The shape of the radiation dose response for DNA double-strand break induction and repair

Stephen Barnard, Simon Bouffler, Kai Rothkamm Genome Integrity 2013, 4:1 (22 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

Review   Open Access

Resolution of complex ends by non-homologous end joining - better to be lucky than good?

Natasha Tiffany Strande, Crystal Ann Waters, Dale A Ramsden Genome Integrity 2012, 3:10 (31 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Open Access Highly Accessed

Pathway choice in DNA double strand break repair: observations of a balancing act

Inger Brandsma, Dik C van Gent Genome Integrity 2012, 3:9 (27 November 2012)

Abstract | Full text | PDF | PubMed

Research   Open Access

Processing of DNA double strand breaks by alternative non-homologous end-joining in hyperacetylated chromatin

Vasilissa Manova, Satyendra K Singh, George Iliakis Genome Integrity 2012, 3:4 (22 August 2012)

Abstract | Full text | PDF | PubMed


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