Editors-in-Chief
- M Prakash Hande, National University of Singapore
- Predrag Slijepcevic, Brunel University, London
- Razqallah Hakem, University of Toronto
- John Petrini, Memorial Sloan-Kettering Cancer Center, New York
Articles
-
Research
Genome Integrity 2013, 4:3 (12 April 2013)Genome-wide distribution of histone H4 Lysine 16 acetylation sites and their relationship to gene expression
-
Research
Genome Integrity 2013, 4:2 (22 March 2013)Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition
-
Review
Genome Integrity 2013, 4:1 (22 March 2013)The shape of the radiation dose response for DNA double-strand break induction and repair
-
Review
Genome Integrity 2012, 3:10 (31 December 2012)Resolution of complex ends by non-homologous end joining - better to be lucky than good?
-
Review
Genome Integrity 2012, 3:9 (27 November 2012)Pathway choice in DNA double strand break repair: observations of a balancing act
-
Research
Genome Integrity 2012, 3:8 (2 November 2012)Gamma-H2AX foci in cells exposed to a mixed beam of X-rays and alpha particles
- View more articles
Aims & scope
Genome Integrity is an open access journal that publishes research on all aspects of genome integrity, the cellular processes underlying maintenance of genome stability, and the effects of instability.
The processes that regulate genome integrity maintenance include sensing, signalling and repair of DNA damage, processing of DNA damage in the context of chromatin and chromosomes, cell cycle checkpoint control and control of apoptosis. Effective maintenance of genome integrity is essential for normal cell division, tissue homeostasis, healthy organismal ageing and prevention of diseases such as cancer. A number of model systems including single cell organisms and various higher plant and animal species, as well as studies of human cells/tissues or patients are required to understand how genome integrity maintenance affects ageing and development of cancer.
Latest review
Review
The shape of the radiation dose response for DNA double-strand break induction and repair
Genome Integrity 2013, 4:1
Article Collections
-
Non-homologous end joining and human disease
Published: 22 August 2012
Last Updated: 22 March 2013
Email updates
Receive periodic news and updates relating to this journal straight to your inbox.
RSS
Comments
View more comments